M. D. Ennis, David W. Old
Oct 13, 1992
Citations
0
Influential Citations
19
Citations
Journal
Tetrahedron Letters
Abstract
Abstract 2-Hydroxymethyl-1,4-benzodioxanes have been shown to be effectively resolved through an enzyme-mediated, stereoselective acylation. Enantiomeric excesses greater than 80% are realized after a single acylation, and enriched material can be upgraded to >96% ee by a second enzymatic resolution.