M. Periasamy, V. D. Rao, M. Seenivasaperumal
Jul 30, 2001
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Influential Citations
7
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Journal
Tetrahedron-asymmetry
Abstract
Abstract Racemic 2,3-diphenylbutane-1,4-diol (±)- 1 is resolved to obtain the corresponding ( R , R )-isomer in 98% e.e. through reaction with ( S )-proline and boric acid. Partially resolved ( R , R )-(−)- 1 and ( S , S )-(+)- 1 have been enriched to obtain samples of 95 and 97% e.e. through reaction with ( S )-proline and boric acid. Diastereomeric 1,4-diphenylbutane-1,4-diol 2 has been purified to obtain the ( R , R )-isomer in 98% e.e. using ( S )-proline and boric acid.