M. Attolini, G. Iacazio, G. Peiffer
Nov 18, 2002
Citations
0
Influential Citations
10
Citations
Journal
Tetrahedron Letters
Abstract
The enzymatic esterification of diethyl (3-hydroxy-1-butenyl) phosphonate 1 with different enzymes has been carried out, and allows the preparation of (S)-1 and (R)-diethyl (3-acetoxy-1-butenyl) phosphonate 2 with very high enantiomeric excess. The absolute conguration of 1 was determined by independent synthesis from (S)-ethyl lactate.