A. Kawachi, Hirofumi Maeda, K. Mitsudo
Oct 1, 1999
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0
Influential Citations
23
Citations
Journal
Organometallics
Abstract
The diastereomeric (amino)fluorosilane 2 is prepared from the prochiral (1-naphthyl)phenyldifluorosilane 5 with optically active bis[(R)-1-phenylethyl]amine (3). The two isomers of 2 can be easily separated due to their large solubility difference in CH3NO2. In addition, 2 undergoes epimerization at the silicon atom in the presence of a catalytic amount of AgF. Stereospecific methylation and the deamination−fluorination of 2 give the enantiomerically pure (1-naphthyl)phenylmethylfluorosilane (1).