W. J. Marsheck, M. Miyano
Sep 25, 1973
Citations
0
Influential Citations
24
Citations
Journal
Biochimica et biophysica acta
Abstract
Abstract Esters of racemic 7-(2− trans -styryl-3-hydroxy-5-oxocyclopentenyl)- n -heptanoic acid, a key intermediate in the total synthesis of natural prostaglandins and their analogues, are subjected to the stereoselective hydrolysis of a Saccharomyces species. The resulting optically resolved enantiomorphs can be used in the chemical synthesis of F- and E-type prostaglandins.