C. Monteiro, C. Afonso, N. Lourenço
Mar 9, 2010
Citations
1
Influential Citations
10
Citations
Journal
Journal of Chemical Education
Abstract
The enzymatic resolution of rac-1-phenylethanol using ethyl myristate as acylating agent and solvent and Candida antarctica lipase B (CAL-B) as biocatalyst was demonstrated with catalyst and medium reuse. Both enantiomers of 1-phenylethanol were isolated by sequential enzymatic reactions and product distillations. From the first enzymatic reaction, (S)-1-phenylethanol was isolated with a 41% yield and 80% enantiomeric excess, and from the second enzymatic reaction, (R)-1-phenylethanol was isolated with a 56% yield and 63% enantiomeric excess.