M. Mamaghani
2002
Citations
0
Influential Citations
6
Citations
Journal
Tetrahedron
Abstract
Abstract Pig's liver esterase (PLE) has been used as a chiral catalyst in the enzymatic kinetic resolution of aromatic substituted norbornene mono-esters, methyl 3- endo -phenylbicyclo[2.2.1]hept-5-ene-2- exo -carboxylate and its endo -counterpart, methyl 3- endo - p -nitro-phenyl-bicyclo[2.2.1]hept-5-ene-2- exo -carboxylate and methyl 3- endo -benzoylbicyclo[2.2.1]hept-5-ene-2- exo -carboxylate. In this study a range of low to high enantioselectivities (83% ee) was observed. The effect of co-solvents has also been examined.