J. Chayen, F. Altmann, L. Bitensky
Apr 25, 1970
Citations
0
Influential Citations
19
Citations
Quality indicators
Journal
Lancet
Abstract
Abstract Biopsy tissue from sixteen patients with carcinoma of the breast was maintained in Trowell's T8 culture medium to which oestradiol, œstrogen antagonists (testosterone and drostanolone), or both oestradiol and drostanolone had been added. This in-vitro test differentiated two types of malignant tissue: five specimens survived well in the medium without additives, but seven did not. These seven specimens survived well in the presence of œstradiol, but not when œstrogen antagonists (alone or with oestradiol) were added.