G. P. Zecchini, M. P. Paradisi, I. Torrini
Nov 11, 1991
Citations
0
Influential Citations
22
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Boc-Pro-Leu-Ψ(NH-SO 2 )-Gly-NH 2 ( 3 ) has been synthesized as the first example of a pseudopeptide incorporating the NH-SO 2 junction. The crystal structure of 3 indicates that the Ψ(NH-SO 2 ) induces a cisoidal (gauche − ) conformation which induces a backbone folding and prevents the H-bonded β-turn found in the parent peptide.