Ramón Badorrey, C. Cativiela, M. D. Díaz-de-Villegas
Jan 27, 1997
Citations
0
Influential Citations
28
Citations
Journal
Tetrahedron
Abstract
Abstract The N -Benzyl imines derived from 2,3-di- O -benzyl- D -glyceraldehyde and 2,3-di- O -isopropylidene- D -glyceraldehyde reacted with phenylmagnesium bromide to afford fully protected aminodiols with total diastereoselectivity. The stereochemical course of the addition reaction depends on the nature of the O -protecting group. These compounds can be easily transformed to enantiomerically pure ( R ) and ( S ) α -phenylglycine.