M. Shareef, Irfan Khan, B. N. Babu
2019
Citations
1
Influential Citations
6
Citations
Quality indicators
Journal
Current medicinal chemistry
Abstract
BACKGROUND Imidazo[2,1-b]thiazole, a well known fused five membered hetrocycle, is one of the most promising and versatile moiety in the area of medicinal chemistry. Derivatives of imidazo[2,1-b]thiazole have been investigated for the development of new derivatives that exhibit diverse pharmacological activities. This fused heterocycle is also a part of a number of therapeutic agents. OBJECTIVE To review the extensive pharmacological activities of imidazo[2,1-b]thiazole derivatives and the new molecules developed between 2000-2018 and usefulness. METHOD Thorough literature review of all relevant papers and patents was conducted. CONCLUSION The present review, covering a number of aspects, is expected to provide useful insights towards the design of imidazo[2,1-b]thiazole based compounds and would inspire the medicinal chemists for a comprehensive and target oriented information to achieve a major breakthrough in the development of clinically viable candidates.