F. Trenti, R. Cox
May 3, 2017
Citations
0
Influential Citations
14
Citations
Journal
Journal of natural products
Abstract
The structure of the fungal phytotoxins known as the phyllostictines has been revised to a series of bicyclic 3-methylene tetramic acids. Genome sequencing of the producing organism Phyllostica cirsii has revealed a biosynthetic gene cluster responsible for the biosynthesis of the phyllostictines, and targeted knockout experiments have proven the link and produced an intermediate.