Yu-Feng Liang, Ke‐Yin Yu, Bin Li
May 15, 2014
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Influential Citations
122
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Quality indicators
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Chemical communications
Abstract
A novel and direct approach to synthesize 1-aminoindole derivatives by Rh(iii)-catalyzed cyclization of 2-acetyl-1-arylhydrazines with diazo compounds via aryl C-H activation has been developed. This intermolecular annulation involving tandem C-H activation, cyclization and condensation steps proceeds efficiently in water, obviates the need of external oxidants, and displays a broad substituent scope.