Sean H. Wiedemann, R. Bergman, J. Ellman
Apr 15, 2004
Citations
0
Influential Citations
31
Citations
Journal
Organic letters
Abstract
A new method for the preparation of 2-substituted oxazolines by rhodium-catalyzed coupling of alkenes with 4,4-dimethyl-2-oxazoline is reported. The oxazoline products are obtained in good yield with excellent selectivity for the linear product. A variety of alkene substitution patterns and functional groups are tolerated. This procedure represents an attractive alternative to hydroesterification because it does not involve the manipulation of CO gas.