Jun He, Yinping Shi, Wan-Min Cheng
Mar 24, 2016
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0
Influential Citations
75
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Quality indicators
Journal
Angewandte Chemie
Abstract
Highly functionalized 4-bromo-1,2-dihydroisoquinolines were synthesized from readily available 4-(2-(bromomethyl)phenyl)-1-sulfonyl-1,2,3-triazoles. A bromonium ylide is proposed as the key intermediate, which can be formed by the intramolecular nucleophilic attack of the benzyl bromide on the α-imino rhodium carbene formed in the presence of the rhodium catalyst.