Jie Ren, Yanzhen Huang, C. Pi
Feb 27, 2021
Citations
0
Influential Citations
13
Citations
Journal
Chinese Chemical Letters
Abstract
Abstract A novel approach for the synthesis of 4-aminoquinazolines has been developed via rhodium(III)-catalyzed [4 + 2] annulation of N-arylbenzamidines with 1,4,2-dioxazol-5-ones. This reaction features excellent regioselectivity, broad substrate scope and high step economy, which would provide the reference for the construction of the fused 4-aminoquinazolines with biologically and pharmacologically active compounds.