A. Q. Hussein, M. El-Abadelah, M. Z. Nazer
1994
Citations
0
Influential Citations
5
Citations
Journal
Heterocycles
Abstract
4-Amino-Δ 2 -1,2,4-oxadiazolines (1) are transformed into the corresponding 2-arylamino-1,3,4-oxadiazoles (5) or thiadiazoles (6) via reaction with phenyl isocyanate (or phenyl isothiocyanate), followed by brief treatment of the resulting adducts (2 and 3) with trifluoroacetic anhydride at ambient temperature. Treatment of compounds (1) with trifluoroacetic anhydride gave 2-trifluoromethyl-1,3,4-oxadiazoles (8)