E. A. Oostveen, H. Plas
Sep 2, 2010
Citations
0
Influential Citations
2
Citations
Journal
Recueil des Travaux Chimiques des Pays-Bas
Abstract
The mechanism of the conversion of pyrimidine into 5-ethyl-2-methylpyridine has been investigated. It has been proved, using the labelled compounds [1,3-15N]pyrimidine, [4,6-14C]pyrimidine and [5-14C]pyrimidine, that this reaction proceeds via a mechanism, in which the pyrimidine ring is fragmentated into two molecules of HCN and one molecule of N-methylacetaldimine. Four molecules of this imine undergo an aldol type condensation leading to 5-ethyl-2-methylpyridine.