P. F. Zabrodskii, V. Germanchuk, V. G. Mandych
2008
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Quality indicators
Journal
Eksperimental'naia i klinicheskaia farmakologiia
Abstract
Experiments on Wistar rats showed that the activation of m-cholinoreceptors by aceclidine (daily administration in a dose of 0.05 LD50, s.c., for 3 days) enhanced the function of Th1 lymphocytes to a greater extent in comparison to Th2 lymphocytes. The blockage of m-cholinoreceptors by the atropin led to a more pronounced suppression of Th2 lymphocytes function in comparison to Th1 cells.