R. Loutzenhiser, P. Aaronson
Feb 1, 2010
Citations
0
Influential Citations
5
Citations
Journal
Hypertension
Abstract
To the Editor: The recent publication by Guan et al1 and the accompanying editorial in a recent issue of Hypertension 2 both state that the findings of Guan et al1 contradict the observations that we published previously concerning the effects of benzamil and amiloride on the myogenic response of the renal afferent arteriole.3 We argue that much of the data in the 2 studies are, in fact, complementary. In Guan et al1 and in our study, benzamil and amiloride did not inhibit the afferent arteriolar myogenic response at concentrations ≤1 μmol/L. We observed no affect of 3 μmol/L of amiloride, whereas Guan et al1 found …