Maw‐Ling Wang, M. Brahmayya, Yu‐Ming Hsieh
Dec 1, 2015
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Influential Citations
4
Citations
Journal
Journal of The Taiwan Institute of Chemical Engineers
Abstract
Abstract The kinetic study for synthesis of 3,5-dimethyl-1-(3-phenylpropyl)-1H-pyrazole was studied successfully by reacting the 3,5-dimethyl pyrazole with 1-bromo-3-phenyl propane under phase transfer catalysis and ultrasonic irradiation conditions using aqueous solution of NaOH (5 g or 0.25 g/ml), excess amount of bromobenzene and tetrahexyl ammonium bromide as a phase transfer catalyst. The reaction was carried out at 40 °C under pseudo-first order conditions and was monitored by gas chromatography (GC). Kinetic reaction found to follow ‘pseudo first order’ rate law. From the experimental data, a rate expression had been developed to explain the kinetic behavior of the reaction from which the apparent rate constant ( k app ) of the organic phase was attained. The effects of agitation speed, amount of sodium hydroxide, effect of quaternary ammonium salts, amount of catalyst and temperature on the reaction were also studied.