Libing Yu, Ruzhou Zhang, Zhiqin Wang
Nov 15, 2001
Citations
0
Influential Citations
5
Citations
Journal
Journal of The Chemical Society-perkin Transactions 1
Abstract
A new and efficient route has been developed to four derivatives of (R)-4-hydroxycyclohex-2-enone (7–10) from one intermediate, 6. These derivatives are useful chiral building blocks in the synthesis of natural products and in asymmetric reactions. The key step is a stereoselective intramolecular ene reaction with 4 A MS as the Lewis acid and catalyst.