T. Janecki, Tomasz Wąsek
Jan 26, 2004
Citations
0
Influential Citations
29
Citations
Journal
Tetrahedron
Abstract
Abstract 3-Methylidenechroman-2-ones, or their rearrangement products 3-methylchromen-2-ones, were efficiently synthesized by Michael addition of various nucleophiles to 3-diethoxyphosphorylchromen-2-ones followed by Horner–Wadsworth–Emmons reaction of the adducts with formaldehyde. Relative configuration and conformation of the intermediate adducts were studied using NMR spectroscopy and semiempirical PM3 calculations.