S. Modha, J. Trivedi, Vaibhav P Mehta
Jan 7, 2011
Citations
0
Influential Citations
34
Citations
Journal
The Journal of organic chemistry
Abstract
An improved and convenient methodology for the synthesis of asymmetrically substituted pyrazines starting from 3,5-dichloropyrazin-2(1H)-ones has been elaborated. Several nucleoside analogues have been synthesized containing the pyrazine core as the organic base coupled with the sugar via a triazole linkage. The beneficial effect of microwave irradiation throughout the sequence has been demonstrated.