Mahesh Puthanveedu, V. Polychronidou, A. Antonchick
Apr 23, 2019
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0
Influential Citations
19
Citations
Journal
Organic letters
Abstract
A metal-free, regioselective C-H functionalization of heteroaromatic N-oxides has been developed. The method enables the synthesis of various benzylated and alkynylated N-heterocycles in a transition-metal-free manner employing organosilanes as coupling partners. The unanticipated reactivity has been exploited for the synthesis of a number of symmetrical disubstituted acetylenes from ethynyltrimethylsilane via carbon-silicon bond metathesis.