Allyn T. Londregan, D. Piotrowski, Jun Xiao
Nov 5, 2013
Citations
0
Influential Citations
21
Citations
Journal
Synlett
Abstract
Abstract Pyridine-N-oxides are often used as reactive precursors in the syntheses of substituted pyridines. Isolation and subsequent reduction of the associated pyridine-N-oxide intermediates can be challenging. We have discovered that tetrahydroxydiboron functions as a mild, versatile, and remarkably selective reducing agent for pyridine-N-oxides and may be used in an in situ fashion, thus obviating the isolation of N-oxide-containing intermediates