J. Kiel, J. Parker, J. Alls
Oct 31, 1991
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Journal
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 13: 1991
Abstract
In this paper, we present the conditions for biosynthesis of diazomelanin and diazoluminopereua, and Bacillu anthracig (nonpathogenic Sterne strain). Diazomelanin (DM) is the fundamental polymer resulting from the interactions of 3-diazotyrosine with itself and diazoluminomelanin is a brown to black highly anionic polymer resulting from the further interaction of DM with luminol. The aforementioned bacteria formed the polymers in nutrient agars containing nitrate and 3-amino-L-tyrosine for DM and, additionally, luminol (5-amino-2,3-dihydro-1,4phthalazinedione) for DAM. B. coli produced the polymer under microaerophilic conditions [4] and the Bacillug spp. produced it under aerobic conditions. DAM is a long-term luminescent material that luminesces when treated with an oxidant and a source of carbon dioxide [1,2]. Its luminescence is enhanced by heat and radiofrequency radiation (2,3]. Because DAM was produced intracellularly, the process is a