A. Sertoli, S. Francalanci, S. Giorgini
Jul 1, 1994
Citations
0
Influential Citations
12
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Journal
Contact Dermatitis
Abstract
Both occupational and non-occupational textile allergic contact dermatitis have increasingly been reported (1-6). Disperse dyes are widely used by the textile industry (7) and are the most important allergens in non-occupational clothing contact dermatitis, which is caused mainly by azo dyes such as Disperse Yellow 3, Disperse Red 1, Disperse Orange 3, Disperse Blue 124 and Disperse Blue 106 (cross-reacting with the last), but also by anthraquinone dyes such as Disperse Blue I and Disperse Blue 3 (3-5, 8-10). These dyes have been reported to be moderate-strong sensitizers (9, 10). Diagnosis of clothing dermatitis is often difficult, because it is characterized by considerable clinical polymorphism, resembling atopic dermatitis, seborrheic dermatitis, inverse psoriasis, lichen simplex, etc. (2, II, 12). In addition, contact sensitization to disperse azo dyes is unreliably detected by p-phenylenediamine in the standard series, and patch tests with additional textile series are frequently needed to confirm the diagnosis (2, 3, 8, 11, 12). Since 1989, 3 disperse dyes have been added to the GIRDCA standard series: Disperse Yellow 3, Red I and Blue 124, all 1'% pet. (6, 8, 9, 11). In our experience, reactions of some intensity to patch tests with disperse dyes at I o;,, pet. can sometimes be observed (particularly to Disperse Blue 124), associated with excited skin syndrome and flare-up of dermatitis. The aim of this study carried out after preliminary observations published elsewhere (13), from May 1992 to July 1993, was to evaluate patch tests with: (i) reduced concentrations of these disperse dyes; (ii) a new mix containing disperse dyes previously added to the GIRDCA standard series and, in addition, Disperse Orange 3.