T. Nakagawa, Y. Oda, A. Shibukawa
Apr 25, 1988
Citations
0
Influential Citations
45
Citations
Journal
Chemical & pharmaceutical bulletin
Abstract
Electrokinetic chromatography was used to determine cefpiramide (CPM) in human plasma, using antipyrine (AP) as an internal standard. A plasma sample was introduced into a fused silica capillary. Then high voltage was applied between the ends of the capillary dipped in a phosphate buffer solution containing sodium dodecyl sulfate above critical micellar concentration (CMC). The CPM and AP were separeted from each other and from plasma proteins within 5 min. The calibration line indicated good linearity in the concentration range over 10 to 300 μg/ml.