H. Iwamoto, Y. Kondo, Takefumi Kawatani
Aug 4, 2003
Citations
0
Influential Citations
4
Citations
Journal
Tetrahedron Letters
Abstract
Abstract 4-Aza-5α-androstanone( 1α ) and 4-aza-5β-androstanone( 1β ) were synthesized in order to obtain the NMR shielding parameters for the secondary amine group. A combination of the electric field effect and the anisotropy of the magnetic susceptibility of the CN bond can successfully reproduce the observed SIS values for these androstanes. Drastic chemical shift change of protons near-by nitrogen atom of ammonium salt was observed and shielding parameter for the secondary ammonium group was also obtained.