M. Turner, B. W. Smith, E. Haslam
1975
Citations
1
Influential Citations
18
Citations
Journal
Journal of the Chemical Society. Perkin transactions 1
Abstract
The conversion of 3-dehydroquinate (1,3,4-trihydroxy-5-oxocyclohexanecarboxylate)(8) into 3-dehydroshikimate (4,5-dihydroxy-3-oxocyclohex-1-enecarboxylate)(9) involves the syn-elimination of the elements of water; this observation confirms earlier work on the reaction. Studies on the 3-dehydroquinate synthetase reaction show it to possess a stereospecificity with respect to the C-7 protons of the substrate 3-deoxy-D-arabino-heptulosonic acid 7-phosphate (7).