E. Baciocchi*, M. Bietti, M. Mattioli
Dec 1, 1993
Citations
1
Influential Citations
33
Citations
Journal
Journal of Organic Chemistry
Abstract
A kinetic study of the side-chain oxidation of α-substituted 4-methoxytoluenes (4-MeOPhCH 2 R, R=H, Me, OH, OMe, OAc, CN) by K 5 Co III W 12 O 40 .11H 2 O (Co(III)W) in AcOH/H 2 O (55:45) has been carried out. The reactions follow complex kinetics, suggesting that both the electron transfer and the radical cation deprotonation steps influence the reaction rate. A careful kinetic analysis has allowed the determination of the values of k 1 , the rate constant for the electron transfer step, and of k -1 /k 2 , the ratio between the rate constant of the back electron transfer and the one of the deprotonation of the cation radical