T. Salama, S. S. Elmorsy
Oct 1, 2011
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0
Influential Citations
10
Citations
Journal
Chinese Chemical Letters
Abstract
Abstract A combination of tetrachlorosilane (TCS) and phenol in dichloromethane was found to be an efficient reagent for hydrochlorination of α , β -unsaturated ketones to afford the corresponding β -chloroketones in good yield at ambient temperature. Reactions of the titled compounds with TCS-NaN 3 as well as with nitriles utilizing TCS-ZnCl 2 to give 1,5-disubstituted tetrazole derivatives or β -amido ketones respectively are also described.