Guangbin Jiang, Chuanle Zhu, Jianxiao Li
Apr 3, 2017
Citations
0
Influential Citations
49
Citations
Journal
Advanced Synthesis & Catalysis
Abstract
A regio- and stereoselective method for the preparation of (Z)-vinyl thiocyanate derivatives by silver-catalyzed thiocyanation of haloalkynes is reported. This method features practical, free of ligand, broad substrate scope, excellent stereoselectivity and gram-scale synthesis. Significantly, the halogen atom of haloalkynes is retained, which allows the synthesis of 2,5-diphenylthiophene, thiazol-2-amine and trifluoromethyl sulfides derivatives via simple transformation.