Haiyun Peng, Yu Zhang, Yang Zhu
Sep 18, 2020
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0
Influential Citations
11
Citations
Journal
The Journal of organic chemistry
Abstract
We report the synthesis of 4-(furan-2-yl)-3,4-dihydro-2H-pyrrol-2-one derivatives. In this approach, two core structures of furan ring and 3,4-dihydro-2H-pyrrol-2-one are constructed via silver(I)-catalyzed cascade cyclization/cyclopropanation/ ring-cleavage/nucleophilic substitution reaction of enynones with enamines. A reasonable mechanism has been proposed. This method possesses some advantages such as high chemoselectivity, mild reaction conditions, simple operation and short reaction time.