M. Anteunis, C. Becu, Frank Becu
Sep 1, 2010
Citations
0
Influential Citations
2
Citations
Journal
Bulletin des Sociétés Chimiques Belges
Abstract
The use of trimethylsilyl cyanide as a potent ”in situ“ silylating agent and its compatibility with most classical functionalities employed during solution phase peptide syntheses allows repetitive peptide chain elongations (including linear Head-to-Tail) with a minimum of chemical steps and manipulations. The outstanding features are: the upscaling facilities, the simplicity and the high purity of the final peptides exempt of stereomutation.