L. Dudycz, G. Wright
1984
Citations
0
Influential Citations
44
Citations
Journal
Nucleosides, Nucleotides & Nucleic Acids
Abstract
Abstract Combination of bis(trimethylsilyl)acetamide as a silylating reagent and trimethylsilyl trifluoromethanesulfonate as a catalyst forms an exceptionally stable system for a facile one-pot preparation of 6-oxopurine ribonucleosides. The 7β isomer of the ribonucleosides, formed first, is converted into the 9β isomer presumably via the 7,9-diribonucleoside. The procedure affords both 7β and 9β isomers, but finally yields the 9β isomer as the main product.