M. Potier, A. Chantôme, Virginie Joulin
Jan 1, 2011
Citations
0
Influential Citations
50
Citations
Journal
British Journal of Pharmacology
Abstract
BACKGROUND AND PURPOSE The 1‐O‐octadecyl‐2‐O‐methyl‐sn‐glycero‐3‐phosphocholine (edelfosine) is an ether‐linked phospholipid with promising anti‐cancer properties but some side effects that preclude its full clinical therapeutic exploitation. We hypothesized that this lipid could interact with plasma membrane ion channels and modulate their function.