Sherif Elawa, Robin Mirdell, S. Farnebo
Nov 27, 2019
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Influential Citations
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Quality indicators
Journal
Skin Research and Technology
Abstract
Methyl nicotinate (MN) induces a local cutaneous erythema in the skin and may be valuable as a local provocation in the assessment of microcirculation and skin viability. The mechanisms through which MN mediates its vascular effect are not fully known. The aim of this study was to characterize the vasodilatory effects of topically applied MN and to study the involvement of nitric oxide (NO), local sensory nerves, and prostaglandin‐mediated pathways.