T. Funaki, Shunsuke Kon, K. Tanabe
Sep 1, 2013
Citations
3
Influential Citations
31
Citations
Journal
Molecular Biology of the Cell
Abstract
SMAP2 is an Arf GAP and modulates clathrin-coated vesicle formation. SMAP2-deficient male mice exhibited globozoospermia due to acrosome deformation. In SMAP2(−/−) spermatids, budding of proacrosomal vesicles from the TGN was distorted and clathrin traffic–related molecules such as CALM and syntaxin2 were mislocated.