S. Roopan, F. N. Khan
Jul 1, 2011
Citations
0
Influential Citations
52
Citations
Journal
Medicinal Chemistry Research
Abstract
An efficient, practical, and eco-friendly method of preparation of 9-chloro-6,13-dihydro-7-phenyl-5H-indolo[3,2-c]-acridines (3a–c) is reported by Friedlander condensation of 2-amino-5-chlorobenzophenone 1 and active methylene compound 3,4-dihydro-2H-carbazol-1(9H)-ones (2a–c) in the presence of SnO2 nanoparticles under microwave irradiation. Indoloacridines, 3a–c, were screened for their in vitro hemolytic activity, on human erythrocytes and cytotoxicity, on HeLa and Vero cells.