Cai Chun
2004
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Journal
Fine Chemical Intermediates
Abstract
The synthesis of methyl 4-butyrylamino-3-methy-5-nitrobenzoate was investigated and improved, using mixing acid of nitric acid and sulfuric acid in nitration instead of concentrated nitric acid as well. The process was satisfactory in respect of high yield above 80%, The new method has some advantages, such as low production cost, high quality and yield.