Biao Lu, Xiaoan Xie, Jidong Zhu
Dec 1, 2005
Citations
0
Influential Citations
6
Citations
Journal
Chinese Journal of Chemistry
Abstract
Reduction of azides to amines without touching benzyl, t-butyldimethylsilyl, t-butyldiphenylsilyl, trityl and tetrahydropyranyl ether protecting groups, CC double and triple bond, as well as aromatic bromide and nitrile functional groups, was achieved using sodium amalgam as a reducing reagent in methanol at temperature from −40 °C to room temperature. However, ester group was reduced under this condition.