B. P. Bandgar, V. T. Kamble, S. Bavikar
Apr 1, 2007
Citations
0
Influential Citations
11
Citations
Journal
Journal of The Chinese Chemical Society
Abstract
Sodium tetrafluoroborate (NaBF 4 ) is found to catalyze the three component condensation of an aldehyde, 1,3-dicarbonyl compound and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones and thiones in high yields. This method is very useful for the synthesis of a wide range of 3,4-dihydropyrimidin-2(1H)-ones and thiones from aromatic, heterocyclic, α,β-unsaturated aldehydes and aliphatic aldehydes.