Lan-Ying Qin, A. G. Cole, A. Metzger
Jan 28, 2009
Citations
0
Influential Citations
6
Citations
Journal
Tetrahedron Letters
Abstract
A general solid-phase synthesis of 1,2,5-trisubstituted imidazolidin-4-ones is described. The key synthetic transformation incorporates a microwave-assisted condensation of an α-amino amide on solid support with an aldehyde in solution to give the corresponding resin-bound imidazolidin-4-one in a simple one-pot procedure.