Y. Hoshina, S. Ikegami, K. Fujimoto
Dec 26, 2005
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0
Influential Citations
2
Citations
Journal
Tetrahedron Letters
Abstract
2,3-Diphenylpropionic acid library for VLA-4 antagonist was synthesized on solid-phase. Comparison of the two synthetic routes via an orthogonal generation of two aromatic amino functional groups are discussed. From this work, several compounds were identified as potent VLA-4 antagonists.