Iteng Ng-Choi, Marta Soler, Vanessa Cerezo
Aug 1, 2012
Citations
0
Influential Citations
17
Citations
Journal
European Journal of Organic Chemistry
Abstract
A microwave-assisted solid-phase Suzuki–Miyaura reaction has been employed for the synthesis of 5-arylhistidine-containing peptides. In particular, sequences containing a 5arylhistidine at the 1- or 4-positions have been designed based on lead antimicrobial peptides. The cross-coupling involved the arylation of a resin-bound 5-bromohistidine with an arylboronic acid in solution under microwave irradiation.