Cheryl L. Judy, W. Acree
Nov 1, 1985
Citations
0
Influential Citations
5
Citations
Journal
International Journal of Pharmaceutics
Abstract
Solubilities are reported for p-tolylacetic acid in binary mixtures of cyclohexane with n-hexane, n-heptane, n-octane and isooctane at 25 °C. The results are compared to the predictions of equations developed previously for solubility in systems of purely non-specific interactions, with the carboxylic acid considered as either monomeric or dimeric molecules in solution. The dimer model provided the more accurate predictions, with a maximum deviation of 5.6% between observed and predicted solubility in all systems studied.