A. Lata, R. Satsangi, V. K. Srivastava
1982
Citations
0
Influential Citations
1
Citations
Quality indicators
Journal
Polish journal of pharmacology and pharmacy
Abstract
Seventeen new 1-(2'-methyl-6'-methoxyquinoline-4'-yl-amino)-2-methyl-4-arylideneimidazol-5-ones have been synthesized by the condensation between the respective azlactones (prepared by the well known Erlenmeyer azlactone synthesis) and 2-methyl-4 hydrazino-6-methoxy-quinolines. The compounds have been found to possess anticonvulsant activity against maximal electroshock seizures and chemoshock induced seizures and the analgesic activity. Some qualitative structure activity relationship has been established.