R. Stretton, T. Manson
Mar 1, 1973
Citations
0
Influential Citations
52
Citations
Journal
The Journal of applied bacteriology
Abstract
Summary. A series of nitro compounds studied inhibited Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa, bronopol being the most active derivative. Bronopol causes some membrane damage. A consideration of its action on enzyme activity, reaction with cell constituents and chemical reaction with cysteine, glutathione and proteins suggests that the oxidation of thiol groups to disulphides may be its primary action.